ISBN: 978-0-6450017-1-6
Exon Publications, Brisbane, Australia

Helder I. Nakaya, PhD (ed)
Department of Clinical and Toxicological Analyses, School of Pharmaceutical Sciences, University of Sao Paulo, Sao Paulo, Brazil


Today, a single laboratory can generate a vast amount of biological data. There is a wealth of data already available in public databases, which makes the modern life sciences almost dependent on bioinformatics. This book brings together an international team of experts to discuss the state-of-the-art from several fields of bioinformatics, from the automatic identification and classification of viruses to the analysis of the transcriptome of single cells and plants, including artificial intelligence algorithms to discover biomarkers and text mining approaches to help in the interpretation of the findings. Machine learning, pattern discovery and analysis, error correction, Bayesian inference and novel computational techniques to discover chromosomal rearrangements continue to play crucial roles in biological discovery, and all of them are explored in chapters of this book. In sum, this book contains high-quality chapters that provide excellent views into key topics of current bioinformatics research, topics that should remain important for the next several years.

Published: 2021-03-20


João Carlos Setubal

Page vii


Helder I. Nakaya

Pages ix-x


Pages xi-xiii

Text Mining Gene Selection to Understand Pathological Phenotype Using Biological Big Data

Christophe Desterke, Hans-Kristian Lorenzo, Jean-Jacques Candelier

Pages 1-18

Single-Cell RNA Sequencing Procedures and Data Analysis

Markus Wolfien, Robert David, Anne-Marie Galow

Pages 19-35

Bayesian Inference of Gene Expression

Víctor Jiménez-Jiménez, Carlos Martí-Gómez, Miguel Ángel del Pozo, Enrique Lara-Pezzi, Fatima Sanchez-Cabo

Pages 65-87

Comprehensive Evaluation of Error-Correction Methodologies for Genome Sequencing Data

Yun Heo, Gowthami Manikandan, Anand Ramachandran, Deming Chen

Pages 89-108

Plant Transcriptome Assembly: Review and Benchmarking

Sairam Behera, Adam Voshall, Etsuko Moriyama

Pages 109-130

WeMine Aligned Pattern Clustering System for Biosequence Pattern Analysis

En-Shiun Annie Lee, Peiyuan Zhou, Andrew K.C. Wong

Pages 131-150



Pages 183-188