Mpox, also known as Monkeypox, is a viral disease that affects both humans and animals, primarily caused by the Monkeypox virus. This article provides information about Mpox, serving as a valuable resource for the public. The article begins with an introduction to Mpox, explaining its origins and primary causes of infection. It covers the different strains of the virus and discusses the various risk factors associated with the disease. The article explains how common Mpox is, the signs and symptoms to watch for, and how the virus spreads. It details the methods used for diagnosing Mpox and the pathophysiology of the disease. Treatment options, primarily focusing on supportive care, are discussed, along with preventive measures to reduce the risk of infection. All information is presented in simple terms to ensure it is understandable for all readers. This is part of the “Public Education Series” initiative of Exon Publications.