Depression is a serious mood disorder that significantly impacts how a person feels, thinks, and handles daily activities. This article provides information about depression, serving as a valuable resource for patients, their loved ones, and the general public. The article begins with an introduction to depression, explaining what it is and its different types. It covers the patterns of depression and distinguishes between normal mood changes and clinical depression. The symptoms and causes of depression are discussed in detail, along with the various risk factors associated with the condition. The article also explains how depression is diagnosed and explores the different treatment and management options available, including medication, psychotherapy, and lifestyle changes. It concludes by emphasizing the importance of early detection, appropriate treatment, and supportive measures to improve the quality of life for those affected by depression. All information is presented in simple terms to ensure it is understandable for all readers. This is part of the “Public Education Series” initiative of Exon Publications.