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Much has been written about the utility of FDG PET/CT (fluorodeoxyglucose positron emission tomography/computed tomography) in frequently encountered malignancies such as lung cancer, breast cancer, and gastrointestinal cancers. Although less common, FDG PET/CT can be a useful modality in the evaluation and staging of cancers of the male GU (genitourinary) tract. Similar to its application with the more common malignancies, FDG PET/CT can provide helpful information when evaluating for sites of disease such as recurrent, nodal, and/or metastatic disease in the setting of these GU cancers. This chapter reviews the utility of PET/CT in the evaluation of non-prostate male GU pathologies such as the penis and testicles. Some very rare tumors as well as infectious and/or inflammatory conditions that can affect the GU system are also described.
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