Preface

Multiple sclerosis (MS) is a chronic neurological disorder with potentially devastating, long-term complications. Although not considered a life-threatening, terminal illness, MS is incurable and most therapies may treat only the symptoms, leaving the patient with a reduced quality of life for extended periods of time. Given that the onset of MS can occur as early as the second or third decade of life, patients can be compromised in their lifestyles for many decades. This book focuses on different biological pathways associated with MS and contains current information on the prevalence of MS, novel treatments that target pathophysiology, and new approaches for management of the disorder, as well as general knowledge about the disease process. Basic science research and clinical research continues to make advances into understanding MS. The book focuses on specific deficits related to this autoimmune disorder. Over the last few years, a number of different therapies have gained momentum, and new perspectives on the pathogenesis of MS have been established. The book is divided into two sections that are related to the etiology and treatment of MS, and the pathophysiology and mechanistic pathways underlying the disease. CONTINUE READING…..