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Weijie Li, MD, PHD

Leukemia is a heterogeneous group of hematological malignancies characterized by the proliferation of abnormal lymphoid or hematopoietic cells in the bone marrow, frequently involving peripheral blood, spleen, and lymph nodes. Leukemia is the 10th most common human malignancy, with over 60,000 new cases diagnosed in the United States every year and approximately 1.5% of people diagnosed at some point during their lifetime. Tremendous advances have been made in the biology and genetics of leukemia during the past several decades, which have translated into significantly improved clinical management and survival outcome. This 10-chapter book provides the most up-to-date information on important topics such as prognostic and predictive biomarkers, new World Health Organization (WHO) classification, pharmacogenomics, and measurable (minimal) residual disease (MRD). Also included in this book are in-depth reviews of several interesting leukemia entities, which update these entities from various aspects including etiology, pathogenesis, histopathology, diagnosis, treatments, and clinical outcomes. The WHO classification of tumors has provided a unified tumor classification system enabling people across the world to share their experience, knowledge, and research results. Ongoing research work conducted by many researchers and physicians has been leading to our continuously improved understanding of tumors and the continual production of new editions of WHO classification with updates. CONTINUE READING…..


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