Kidney Function and Other Manifestations of Polycystic Kidney Disease

ABSTRACT
Polycystic Kidney Disease (PKD) is a genetic disorder that leads to the formation of numerous fluid-filled cysts in the kidneys and affects other parts of the body. Genetic mutations disrupt normal cellular functions, leading to uncontrolled cell growth and cyst formation. As these cysts expand, they impair the kidneys' ability to filter waste, resulting in chronic kidney disease and potentially end-stage renal disease. PKD also causes issues beyond the kidneys, such as liver cysts, aneurysms, heart problems, and digestive issues. This chapter explores the impact of PKD on kidney function, and the extrarenal manifestations of the disease.

Cite as: Kidney Function and Other Manifestations of Polycystic Kidney Disease. In: Polycystic Kidney Disease: Public Education. Brisbane (AU): Exon Publications, 2024. Online first 2024 May 28. ISBN: 978-0-6458663-8-4
DOI: https://doi.org/10.36255/kidney-function-other-manifestations-polycystic-kidney-disease